Friday, January 27, 2012

2012 EBF Focus Meeting - Agenda

Day 1 - 12 June 2012

Morning plenary sessions: What's new in Sample Enrichment Technology

Session 1 -   Miniaturization and/or automation of sample preparation techniques?

Goal: This session will focus on recent progress made in automation and/or miniaturization in support of (regulated) bioanalytical sample preparation. This includes but is not limited to liquid handling technologies, micro extraction and chip technologies. The goal of this session is to share and discuss techniques and processes that will facilitate the sample preparation workflow.

                      Coffee break

Session 2 -   How can antibody technology help with sample enrichment for NCE or peptides quantification?

                     Goal: This session will focus the use of antibody capture techiques used to optimise sample enrichment  for Pharmocokinetic and Pharmacodynamic endpoints technologies.

Afternoon plenary sessions: Recent developments in tissue analysis

Session 3 -   Tissue analysis (including micro sampling) and PK/PD

                     Goal: Over the last years, the analytical potential offered by modern MS technology or  immunological approaches opened new avenues in the analysis of non standard matrices for PK, TK or PK/PD reasons. In this session we invite scientist to share their experience or observed scientific, analytical or regulatory hurdles when applying these new technologies. Both MS and LBA scientist will be welcomed.

Coffee break

Session 4 -   Is Tissue Imaging approaching quantitative bioanalysis expectations?

                     Goal: The goal of this session is to highlight & discuss the advances and current/potential future use of Tissue Imaging approaches as quantitiative bioanalytical tools in a regulated environment.

Day 2 - 13 June 2012

Morning breakout sessions: Focus on LC-MS/MS: Miniaturization and diversification in LC – MS interfacing

Session 5 -   Miniaturization of LC using ‘conventional’ MS Ionization techniques

                     Goal: Advances made in LC miniaturization, such as microbore and capilllary LC, CE, and chip techniques, is opening new possibilities for the bioanalytical scientist. Together with these new possibilities come new challenges. In this session, thoughts and experiences with these techniques will be shared with the aim to enhance the toolset in the (regulated) bioanalytical laboratory and improve problem solving capability.

Coffee break

Session 6 -   Alternative MS-interfaces for quantitative bioanalysis

                     Goal: The last 5 years may have been one of the most exciting periods for the bioanalytical scientist with (historically less robust) alternative MS-interfaces  (to the commonly used ESI and APCI) coming avalailbe to their fullest potential for quantitative bioanalysis. In this session, we aim at providing examples of these alternative MS-interfaces  and want to stimulate discussions to enhance their application in (regulated) quantitative bioanalysis.

Note: Some session will/may include a panel discussion

Morning Breakout Sessions: Focus on Ligand Binding Assays: Emerging platforms in support of LBA

Session 7 -   Recent new technologies – Methodologies

                     Goal: As the industry looks at options beyond traditional single-plate ELISAs  to achieve greater dynamic ranges, analyse multiple analytes or exploit new reporting systems; what are the technology options available (e.g. Flow Cytometry, multiplex analysers etc)? The goal of this session is showcase & discuss the emerging new LBA technologies & novel LBA methodologies for use in a regulated bioanalysis setting.

Coffee break

Session 8 -   Recent new technologies – Applications and validation approaches

                     Goal: How are methods being validated on new technology platforms? This session aims to identify and discuss best practices for the validation package requirements of novel LBA applications - are these bespoke or can traditional ELISA method validation packages be used?

Afternoon plenary session: Global Bioanalysis Consortium Updates

Session 9 -   GBC feedback session

                     Goal: Discuss and provide feedback on the progress made in global harmonization of the bioanalysis  guidelines (GBC). The intention is to invite 4-5 Harmonization team leads (or a regional representative from those teams) to present the progress of their teams and to engage with delegates for input and feedback.

Sunday, January 15, 2012

Call for Speakers & Posters: EBF 3rd Focus Meeting

EBF - European Bioanalysis Forum 3rd Focus Meeting “Hatching”
Emerging Technologies Approaching the Regulated Bioanalysis Laboratory
12-13 June 2012 Sheraton, Brussels, Belgium

Almost 200 scientists met in Brussels in 2011 for the 2nd EBF Focus meeting on peptide and protein analysis with MS technologies ("Large meets Small"). This year again the EBF is pleased to announce that sponsorship for its 3rd Focus meeting is open. In 2012, we will focus our attention on Emerging Technologies approaching the Regulated Bioanalysis Laboratory.
In the last 5 years, we have seen an explosion of new technologies and platforms maturing and becoming available to the bioanalytical scientist. Parallel to this, regulatory requirements for bioanalysis are developing at a similar pace.
With scientific developments and regulatory expectations not always in concert, our 3rd Focus meeting aims to connect on the potential of a broad array of new technologies. We will provide a scientific hub for the development of strategies which may enable the application of these emerging technologies to their full potential in regulated bioanalysis.

Plenary session
  • What’s new in 'Sample Enrichment Technology'
    • Miniaturization and/or automation of sample preparation techniques?
    • How can antibody technologies help with sample enrichment for quantification?
  • Recent developments in tissue analysis
    • Tissue analysis (including micro sampling) and PK/PD
    • Is Tissue imaging approaching quantitative bioanalysis expectations?
  • Global Bioanalysis Consortium (GBC) feedback session
Breakout sessions
  • Small molecules: miniaturization and diversification in LC-MS interfacing
    • Miniaturization of LC using ‘conventional’ MS ionization techniques
    • Alternative MS-interfaces for quantitative bioanalysis
  • Macro molecules: Emerging platforms in support of LBA
    • Recent new technologies Methodologies
    • Recent new technologies Experiences with applications and validations
Each session intends to have 4 speakers (1 keynote of 30 minutes and 3 contributions of 20 minutes). For details on the goals and objectives of each session, please visit the conference website at

Potential speakers, please submit the title and abstract of your presentation (before 31 March 2012) to conference address:, attaching a filled out oral presentation submission form available on the conference website. Acceptance of your presentation will be communicated before 15 April 2011.

There will be room for approx. 30 posters. Please submit the title and abstract of your poster (before 15 May 2012) to conference address:, attaching a filled out poster presentation submission form available on the conference website. Supported Poster format is Portrait (size A0).

Benno Ingelse (MSD), Arjen Companjen (Crucell), John Smeraglia (HLS), Hans Mulder (Astellas), Margarete Brudny-Kloeppel (Bayer Healthcare), Peter van Amsterdam (Abbott Healthcare Products), Neil Henderson (AstraZeneca) & Philip Timmerman (Janssen Research & Development)

Christina Smith, Bavalan Bioconference

The conference is organised as a non-profit event by European Bioanalysis Forum VZW